Alterations in BDNF (brain derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) serum levels in bipolar disorder: The role of lithium
- Resmi, Halil
- Tunca, Zeliha
- Ozerdem, Aysegul
- Ceylan, Deniz
- Yalcin, Yaprak
- Can, Gunes
- AYDEMİR, ÖMER
- Cengisiz, Cengiz
- Doyurana, Kerim
- AKAN, PINAR
- ERGÖR, GÜL
Publication date
September 2014
DOIAbstract
Objective: Brain-derived neurotrophic factor (BDNF) has been consistently reported to be decreased in mania or depression in bipolar disorders. Evidence suggests that Glial cell line-derived neurotrophic factor (GDNF) has a role in the pathogenesis of mood disorders. Whether GDNF and BDNF act in the same way across different episodes in bipolar disorders is unclear
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