CXCL-8-dependent and -independent neutrophil activation in COPD:experiences from a pilot study of the CXCR2 antagonist danirixin
- Keir, Holly R.
- Richardson, Hollian
- Fillmore, Christina
- Shoemark, Amelia
- Lazaar, Aili L.
- Miller, Bruce E.
- Tal-Singer, Ruth
- Chalmers, James D.
- Mohan, Divya
DOIAbstract
The implications of these findings are significant for development of CXCR2 antagonists and other mechanisms targeting neutrophil activation or NETosis, suggesting that IL-8-dependent mechanisms will only work in a subset of COPD patients https://bit.ly/32SeisO.</p
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