Exploring water, sanitation, and hygiene coverage targets for reaching and sustaining trachoma elimination: G-computation analysis
- Sullivan, K.M.
- Nassirou, B.
- Harding-Esch, E.M.
- Keil, A.P.
- Freeman, M.C.
- Batcho, W.E.
- Bio Issifou, A.A.
- Bucumi, V.
- Bella, A.L.
- Epee, E.
- Bobo Barkesa, S.
- Seife Gebretsadik, F.
- Sanha, S.
- Kalua, K.M.
- Masika, M.P.
- Minnih, A.O.
- Abdala, M.
- Massangaie, M.E.
- Amza, A.
- Kadri, B.
- Mpyet, C.D.
- Olobio, N.
- Badiane, M.D.
- Elshafie, B.E.
- Baayenda, G.
- Kabona, G.E.
- Kaitaba, O.
- Simon, A.
- Al-Khateeb, T.Q.
- Mwale, C.
- Bakhtiari, A.
- Westreich, D.
- Solomon, A.W.
- Gower, E.W.
DOIAbstract
BACKGROUND: Trachoma is the leading infectious cause of blindness. To reduce transmission, water, sanitation, and hygiene (WaSH) improvements are promoted through a comprehensive public health strategy. Evidence supporting the role of WaSH in trachoma elimination is mixed and it remains unknown what WaSH coverages are needed to effectively reduce transmission. METHODS/FINDINGS: We used g-computation to estimate the impact on the prevalence of trachomatous inflammation-follicular among children aged 1-9 years (TF1-9) when hypothetical WaSH interventions raised the minimum coverages from 5% to 100% for "nearby" face-washing water (<30 minutes roundtrip collection time) and adult latrine use in an evaluation unit (EU). For each scenario, we es...
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