Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used to map oxygen concentrations in hypoxic tissue. However, validation of pO2-measurements in vivo is difficult. In this study, an oxygen consuming phantom simulating oxygen perfusion in tissue is presented. The phantom consists of a hemodialysis filter of which the outer compartment is filled with a gel containing viable yeast cells. pO2-images reveal oxygen consumption by the yeast cells after injection of a bolus of oxygen rich hexafluorobenzene in the fibers of the hemodialysis filter. The developed phantom can be used for validation of Fluor-19 MRI oximetry
Hypoxia is a typical hallmark of many solid tumors and often leads to therapy resistance and the dev...
AbstractQuantifying oxygenation in viable tumor remains a major obstacle toward a better understandi...
Item does not contain fulltextAbstract Background. Assessing hypoxia with oxygen probes provides a s...
Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used t...
This study presents a reproducible phantom which mimics oxygen-consuming tissue and can be used for ...
Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used t...
Objective: This study presents a reproducible phantom which mimics oxygen-consuming tissue and can b...
The impact of the partitioning of oxygenation markers (perfluorocarbons) between blood and tissue in...
In (FMRI)-F-19 oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenatio...
The aim of this study was to develop an MRI fluorocarbon oximetry technique using snapshot inversion...
In cancer therapy, tumour hypoxia is an important predictor of disease progression, treatment outcom...
Oxygen monitoring is a topic of exhaustive research due to its central role in many biological proce...
In ¹⁹F MRI oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenation ma...
Quantifying oxygenation in viable tumor remains a major obstacle toward a better understanding of th...
This thesis investigates a range of techniques designed to measured tumour oxygenation in vivo, and ...
Hypoxia is a typical hallmark of many solid tumors and often leads to therapy resistance and the dev...
AbstractQuantifying oxygenation in viable tumor remains a major obstacle toward a better understandi...
Item does not contain fulltextAbstract Background. Assessing hypoxia with oxygen probes provides a s...
Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used t...
This study presents a reproducible phantom which mimics oxygen-consuming tissue and can be used for ...
Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used t...
Objective: This study presents a reproducible phantom which mimics oxygen-consuming tissue and can b...
The impact of the partitioning of oxygenation markers (perfluorocarbons) between blood and tissue in...
In (FMRI)-F-19 oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenatio...
The aim of this study was to develop an MRI fluorocarbon oximetry technique using snapshot inversion...
In cancer therapy, tumour hypoxia is an important predictor of disease progression, treatment outcom...
Oxygen monitoring is a topic of exhaustive research due to its central role in many biological proce...
In ¹⁹F MRI oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenation ma...
Quantifying oxygenation in viable tumor remains a major obstacle toward a better understanding of th...
This thesis investigates a range of techniques designed to measured tumour oxygenation in vivo, and ...
Hypoxia is a typical hallmark of many solid tumors and often leads to therapy resistance and the dev...
AbstractQuantifying oxygenation in viable tumor remains a major obstacle toward a better understandi...
Item does not contain fulltextAbstract Background. Assessing hypoxia with oxygen probes provides a s...