Dissertação de mestrado em Medicinal ChemistryChromenes are privileged scaffolds as they comprise multiple natural and synthetic derivatives having pharmacological activity, both in vitro and in vivo. Substituted 1-(2-oxo-2H-chromen-3-yl)pyridinium chloride salts were recently prepared from the reaction of an appropriate salicylaldehyde and 1-(cyanomethyl)pyridinium chloride, in two steps. This work presents a study of the reactivity of these salts, to be used as precursors of novel chromene derivatives. In a previous work, 1-(2-oxo-2H-chromen-3-yl)pyridinium chloride salts were found to react with nitrogen nucleophiles as described in the Zincke reaction, yielding 3-aminochromenes. In this study, the reaction with active methylene ...
A simple and convenient domino cycloaromatization approach towards the synthesis of novel benzo[c]ch...
2H-Oxo-chromenyl acrylates and 2H-imino-chromenyl acrylonitriles have been prepared from a salicylal...
Substituted chromenos, dihydropyridines and pyridines have been important in the syntheses of compou...
Dissertação de mestrado em Química MedicinalColorectal carcinoma (CRC) is the second leading cause o...
The reaction of salicylic aldehydes with malononitrile was reinvestigated, and the reaction pathway ...
Tese de doutoramento em Chemistry (especialização em Organic and Biological Chemistry)A investigação...
The Knoevenagel reaction is defined by the condensation of an aldehyde or ketone with a carbon nucle...
A new series of pyrano-chromene and pyrimido pyrano-chromene derivatives were synthesized starting f...
Azomethine ylides, generated from imine-derived O-cinnamyl or O-crotonyl salicylaldeyde and α-amino ...
In an attempt for development of new antimicrobial agents; new series of chromen-2-one, pyrano[3,4-c...
Conselho Nacional de Desenvolvimento Científico e TecnológicoIn the first part of this work, a serie...
Os cromenos, dihidropiridinas e piridinas substituídos têm-se revelado importantes na síntese de com...
[Abstract] A transition-metal-free coupling of triorganoindium reagents with benzopyranyl acetals me...
AbstractA general and easy method for the synthesis of 4,6-disubstituted-3-cyano-2(1H)-iminopyridine...
An improved simple and facile synthesis of chromene derivatives by employing threecomponent one-pot ...
A simple and convenient domino cycloaromatization approach towards the synthesis of novel benzo[c]ch...
2H-Oxo-chromenyl acrylates and 2H-imino-chromenyl acrylonitriles have been prepared from a salicylal...
Substituted chromenos, dihydropyridines and pyridines have been important in the syntheses of compou...
Dissertação de mestrado em Química MedicinalColorectal carcinoma (CRC) is the second leading cause o...
The reaction of salicylic aldehydes with malononitrile was reinvestigated, and the reaction pathway ...
Tese de doutoramento em Chemistry (especialização em Organic and Biological Chemistry)A investigação...
The Knoevenagel reaction is defined by the condensation of an aldehyde or ketone with a carbon nucle...
A new series of pyrano-chromene and pyrimido pyrano-chromene derivatives were synthesized starting f...
Azomethine ylides, generated from imine-derived O-cinnamyl or O-crotonyl salicylaldeyde and α-amino ...
In an attempt for development of new antimicrobial agents; new series of chromen-2-one, pyrano[3,4-c...
Conselho Nacional de Desenvolvimento Científico e TecnológicoIn the first part of this work, a serie...
Os cromenos, dihidropiridinas e piridinas substituídos têm-se revelado importantes na síntese de com...
[Abstract] A transition-metal-free coupling of triorganoindium reagents with benzopyranyl acetals me...
AbstractA general and easy method for the synthesis of 4,6-disubstituted-3-cyano-2(1H)-iminopyridine...
An improved simple and facile synthesis of chromene derivatives by employing threecomponent one-pot ...
A simple and convenient domino cycloaromatization approach towards the synthesis of novel benzo[c]ch...
2H-Oxo-chromenyl acrylates and 2H-imino-chromenyl acrylonitriles have been prepared from a salicylal...
Substituted chromenos, dihydropyridines and pyridines have been important in the syntheses of compou...