Tendon's regeneration is limited, demanding for cell-based strategies to fully restore their functionality upon injury. The concept of magnetic force-based TE(1), generally using magnetic nanoparticles may enable, for example, stem cell stimulation and/or remote control over TE constructs. Thus, we originally propose the development of magnetic cell sheets (magCSs) with tenogenic capability, aimed at promoting tendon's regeneration. A Tenomodulin (TNMD+) subpopulation was sorted from human adipose stem cells (hASCs), using TNMD-coated immunomagnetic beads(2) and used as cell source for the development of magCSs. Briefly, cells were labeled with iron oxide composite particles (Micromod) and cultured for 7 days in α-MEM medium with or w...
Transplantation of genetically engineered neural stem cells (NSCs) into sites of central nervous sys...
Tendon regeneration can be undermined by the formation of fibrous adhesions (scar tissue) between th...
Purpose: Iron oxide based magnetic nanoparticles (MNP) are versatile tools in biology and medicine. ...
Tendons are powerful 3D biomechanically structures combining a few cells in an intrincated and highl...
Tendons are highly specialized load-bearing tissues with very limited healing capacity. Given their ...
Injuries affecting load bearing tendon tissues are a significant clinical burden and efficient treat...
Tendons are mechanosensitive tissues that connect and transmit the forces generated by muscles to bo...
Tendon injuries are a worldwide problem affecting several age groups and stem cell based therapies h...
Tese de Doutoramento - Programa Doutoral Engenharia de Tecidos, Medicina Regenerativa e Células Esta...
First published: 05 December 2019Tendon tissues connect muscle to bone allowing the transmission of ...
The application of magnetic nanoparticles (MNPs) in tissue engineering (TE) approaches opens several...
Magnetotherapy has been receiving increased attention as an attractive strategy for modulating cell ...
The uniform and aligned arrangement of tendon cells is a marker of tendon tissue morphology and the ...
Cell monitoring and cell localization can be potentially achieved by the internalization of magneti...
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the unsatisfactor...
Transplantation of genetically engineered neural stem cells (NSCs) into sites of central nervous sys...
Tendon regeneration can be undermined by the formation of fibrous adhesions (scar tissue) between th...
Purpose: Iron oxide based magnetic nanoparticles (MNP) are versatile tools in biology and medicine. ...
Tendons are powerful 3D biomechanically structures combining a few cells in an intrincated and highl...
Tendons are highly specialized load-bearing tissues with very limited healing capacity. Given their ...
Injuries affecting load bearing tendon tissues are a significant clinical burden and efficient treat...
Tendons are mechanosensitive tissues that connect and transmit the forces generated by muscles to bo...
Tendon injuries are a worldwide problem affecting several age groups and stem cell based therapies h...
Tese de Doutoramento - Programa Doutoral Engenharia de Tecidos, Medicina Regenerativa e Células Esta...
First published: 05 December 2019Tendon tissues connect muscle to bone allowing the transmission of ...
The application of magnetic nanoparticles (MNPs) in tissue engineering (TE) approaches opens several...
Magnetotherapy has been receiving increased attention as an attractive strategy for modulating cell ...
The uniform and aligned arrangement of tendon cells is a marker of tendon tissue morphology and the ...
Cell monitoring and cell localization can be potentially achieved by the internalization of magneti...
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the unsatisfactor...
Transplantation of genetically engineered neural stem cells (NSCs) into sites of central nervous sys...
Tendon regeneration can be undermined by the formation of fibrous adhesions (scar tissue) between th...
Purpose: Iron oxide based magnetic nanoparticles (MNP) are versatile tools in biology and medicine. ...