Mpox vaccination basics

Updated January 31, 2023Mpox (formerly known as monkeypox) is caused by a virus that is related to the virus that causes smallpox. JYNNEOS is a 2-dose vaccine developed to protect against mpox and smallpox infections. People need to get both doses of the vaccine for the best protection against mpox. The second dose should be given 4 weeks after the first dose.Vaccination is an important tool in stopping the spread of mpox. People who are vaccinated should continue to avoid close, skin-to-skin contact with someone who has mpox