Although it is hypothesized that mesenchymal stem cells’ secretome plays a major role in CNS regeneration, little is known on the mechanisms that regulate these actions. In the present work we aimed to assess if the secretome of a population of MSCs isolated from the WJ of the UC (HUCPVCs) was able to modulate neural/glial survival differentiation and proliferation in in vitro and in vivo models. Two approaches were used: (1) primary cultures of neurons and glial cells, were incubated with conditioned media (CM) from HUCPVCs and (2) HUCPVCs or their CM were injected in the dentate gyrus of male Wistar rats. In vitro results revealed that HUCPVCs CM increased cell proliferation in neuronal and glial cells cultures, as well as the s...
Human umbilical cord matrix (hUCM) is considered as a promising source of mesenchymal stem cells (MS...
AbstractCompelling evidence exists that non-haematopoietic stem cells, including mesenchymal (MSCs) ...
Cell transplantation using Mesenchymal stem cell (MSC) secretome have recently been presented as a p...
It was recently shown that the conditioned media (CM) of Human Umbilical Cord Perivascular Cells (HU...
It has been recently reported that mesenchymal progenitor/stem cells isolated from the Wharton’s Jel...
The low regeneration potential of the central nervous system (CNS) represents a challenge for the de...
In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal ce...
The goal of this study was to determine and compare the effects of the secretome of mesenchymal stem...
Transplantation of bone marrow mesenchymal stem cells (BM-MSCs) has been shown to ameliorate the inj...
It has been previously shown that the secretome of Human Umbilical Cord Perivascular Cells (HUCPVCs)...
Introduction: It is hypothesized that administration of stromal/stem cells isolated from the adipose...
In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/ stromal ...
Human neural progenitor cells (hNPC) and human mesenchymal stromal cells (hMSC) have both been repor...
Introduction: The low regeneration potential of the central nervous system (CNS) represents a chall...
We have previously shown that soluble factors derived from mesenchymal stem cells (MSCs) induce olig...
Human umbilical cord matrix (hUCM) is considered as a promising source of mesenchymal stem cells (MS...
AbstractCompelling evidence exists that non-haematopoietic stem cells, including mesenchymal (MSCs) ...
Cell transplantation using Mesenchymal stem cell (MSC) secretome have recently been presented as a p...
It was recently shown that the conditioned media (CM) of Human Umbilical Cord Perivascular Cells (HU...
It has been recently reported that mesenchymal progenitor/stem cells isolated from the Wharton’s Jel...
The low regeneration potential of the central nervous system (CNS) represents a challenge for the de...
In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal ce...
The goal of this study was to determine and compare the effects of the secretome of mesenchymal stem...
Transplantation of bone marrow mesenchymal stem cells (BM-MSCs) has been shown to ameliorate the inj...
It has been previously shown that the secretome of Human Umbilical Cord Perivascular Cells (HUCPVCs)...
Introduction: It is hypothesized that administration of stromal/stem cells isolated from the adipose...
In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/ stromal ...
Human neural progenitor cells (hNPC) and human mesenchymal stromal cells (hMSC) have both been repor...
Introduction: The low regeneration potential of the central nervous system (CNS) represents a chall...
We have previously shown that soluble factors derived from mesenchymal stem cells (MSCs) induce olig...
Human umbilical cord matrix (hUCM) is considered as a promising source of mesenchymal stem cells (MS...
AbstractCompelling evidence exists that non-haematopoietic stem cells, including mesenchymal (MSCs) ...
Cell transplantation using Mesenchymal stem cell (MSC) secretome have recently been presented as a p...