Clinico-Histomorphological Spectrum of TURBT Biopsies of Urinary Bladder Lesions in a Tertiary Care Centre: A Two-Year Retrospective Study

Introduction: The spectrum of diseases that occur in the urinary bladder, range from congenital malformations to inflammatory conditions to neoplasms. Transurethral resection of bladder tumor (TURBT) aims at completely resecting all the visible tumors, whenever feasible. This provides histological staging and grading for further management of such cases. This study aims to evaluate the clinico-histopathological features of TURBT biopsies in a tertiary care hospital. Materials and Methods: This is a retrospective analysis of urinary bladder lesions received in the Department of Pathology, Government Medical College, Srinagar for histopathological examination over a period of 2 years, January 2019 to December 2020.The department received 166 trans-urethral urinary bladder biopsy specimens during this time interval. Results: In our study most common age group was >61 years with 54/166 patients (32.5%) followed by 51-60 years with 44/166 patients (26.5%). Male to female ratio was 3.15:1. The most common microscopic diagnosis was low-grade papillary urothelial carcinoma 72 cases (43.4%) while the least common microscopic diagnosis was squamous cell carcinoma 01 case (0.60%). While in 154 cases of Neoplastic lesions, there were 72 cases of low-grade papillary urothelial carcinoma,67 cases of high-grade papillary urothelial carcinoma. Conclusion: In Indian population, the diagnosed bladder cancer is predominantly urothelial carcinoma with male predominance. Younger patients present with low grade tumors. Early diagnosis is important in the diagnosis of urinary bladder cancer.http://impactfactor.org/PDF/IJTPR/12/IJTPR,Vol12,Issue12,Article8.pd