Background: Intracellular copper homeostasis requires a complex system. It has shown considerable prospects for intervening in the tumor microenvironment (TME) by regulating copper homeostasis and provoking cuproptosis. Their relationship with hepatocellular carcinoma (HCC) remains elusive.Methods: In TCGA and ICGC datasets, LASSO and multivariate Cox regression were applied to obtain the signature on the basis of genes associated with copper homeostasis and cuproptosis. Bioinformatic tools were utilized to reveal if the signature was correlated with HCC characteristics. Single-cell RNA sequencing data analysis identified differences in tumor and T cells’ pathway activity and intercellular communication of immune-related cells. Real-time qP...
Hepatocellular carcinoma (HCC), the most common primary liver cancer, of which ~800,000 new cases wi...
BackgroundThe correlations between cuproptosis and long noncoding RNAs (lncRNAs) with the tumor micr...
BackgroundThe correlations between cuproptosis and long noncoding RNAs (lncRNAs) with the tumor micr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
The role of cuproptosis, a newly discovered form of programmed cell death, remains poorly understood...
Background: Copper metabolism plays an important role in the tumor microenvironment, and cuproptosis...
Hepatocellular carcinoma (HCC) is one of the world’s malignant tumors with high morbidity and mortal...
Copper (Cu) is an essential element of organisms, which can affect the survival of cells. However, t...
Hepatocellular carcinoma (HCC), the most common primary liver cancer, of which ~800,000 new cases wi...
BackgroundThe correlations between cuproptosis and long noncoding RNAs (lncRNAs) with the tumor micr...
BackgroundThe correlations between cuproptosis and long noncoding RNAs (lncRNAs) with the tumor micr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
Background: Intracellular copper homeostasis requires a complex system. It has shown considerable pr...
The role of cuproptosis, a newly discovered form of programmed cell death, remains poorly understood...
Background: Copper metabolism plays an important role in the tumor microenvironment, and cuproptosis...
Hepatocellular carcinoma (HCC) is one of the world’s malignant tumors with high morbidity and mortal...
Copper (Cu) is an essential element of organisms, which can affect the survival of cells. However, t...
Hepatocellular carcinoma (HCC), the most common primary liver cancer, of which ~800,000 new cases wi...
BackgroundThe correlations between cuproptosis and long noncoding RNAs (lncRNAs) with the tumor micr...
BackgroundThe correlations between cuproptosis and long noncoding RNAs (lncRNAs) with the tumor micr...