The intestine is considered to be a vital digestive organ to absorb nutrients and is the largest immune organ, while numerous microorganisms coexist with the host. It is well known that the complex interactions between the gut microbiota and the host’s immune system inevitably affect the function of other organs, creating an “axis” between them. During the past few years, a new technique based mainly on microfluidics and cell biology has been developed to emulate the structure, function, and microenvironment of the human gut, called the “gut-on-chip”. This microfluidic chip provides insight into key aspects of gut function in health and disease, such as the gut–brain axis, gut–liver axis, gut–kidney axis, and gut–lung axis. In this review, ...
In the conventional culture systems in vitro, the challenging organoid approach have recently been o...
Here, we propose an immune-responsive human Microbiota-Intestine axis on-chip as a platform able to ...
Microfluidic organ-on-a-chip models of human intestine have been developed and used to study intesti...
The intestine contains the largest microbial community in the human body, the gut microbiome. Increa...
peer reviewedThe homeostatic relationship between the gut, its microbiome, and the liver is crucial ...
Organ-on-a-chip technology tries to mimic the complexity of native tissues in vitro. Important progr...
International audienceThe gut is a tubular organ responsible for nutrient absorption and harbors our...
It is difficult to model in vitro the intestine when seeking to include crossta...
The human microbiome and its crosstalk with host cells play a critical role in regulating human heal...
The human body is colonized by at least the same number of microbial cells as it is composed of huma...
Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to neurological di...
Synergic efforts in microfabrication processes, cells culture and tissue engineering promoted extrao...
The human gut microbiome is considered an organ in its entirety and has been the subject of extensiv...
Extracellular vesicles (EVs) are a group of membrane vesicles that play important roles in cell-to-c...
The human intestine is a dynamic organ where the complex host-microbe interactions that orchestrate ...
In the conventional culture systems in vitro, the challenging organoid approach have recently been o...
Here, we propose an immune-responsive human Microbiota-Intestine axis on-chip as a platform able to ...
Microfluidic organ-on-a-chip models of human intestine have been developed and used to study intesti...
The intestine contains the largest microbial community in the human body, the gut microbiome. Increa...
peer reviewedThe homeostatic relationship between the gut, its microbiome, and the liver is crucial ...
Organ-on-a-chip technology tries to mimic the complexity of native tissues in vitro. Important progr...
International audienceThe gut is a tubular organ responsible for nutrient absorption and harbors our...
It is difficult to model in vitro the intestine when seeking to include crossta...
The human microbiome and its crosstalk with host cells play a critical role in regulating human heal...
The human body is colonized by at least the same number of microbial cells as it is composed of huma...
Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to neurological di...
Synergic efforts in microfabrication processes, cells culture and tissue engineering promoted extrao...
The human gut microbiome is considered an organ in its entirety and has been the subject of extensiv...
Extracellular vesicles (EVs) are a group of membrane vesicles that play important roles in cell-to-c...
The human intestine is a dynamic organ where the complex host-microbe interactions that orchestrate ...
In the conventional culture systems in vitro, the challenging organoid approach have recently been o...
Here, we propose an immune-responsive human Microbiota-Intestine axis on-chip as a platform able to ...
Microfluidic organ-on-a-chip models of human intestine have been developed and used to study intesti...