L-asparaginase (L-Aspa) is utilized as a part of the therapy in children with acute lymphoblastic leukemia (ALL), achieving remission in 83–95% of the younger patients. Hypersensitivity reactions, as well as liver and pancreatic cytotoxicity, are severe documented side effects. L-Aspa-induced acute pancreatitis (AP) has been observed in 2.5–16% of treated patients. Patients with mild pancreatitis may be retreated with L-Aspa if they have no clinical symptoms within 48 hours, amylase and lipase levels are less than three times the normal’s upper limit, and there is no evidence of pseudocysts or necrosis on imaging. It is crucial to monitor patients under L-Aspa therapy, through careful observation of clinical signs and laboratory follow-up, ...
Asparaginase (ASP)-associated pancreatitis (AAP) occurs during acute lymphoblastic leukemia treatmen...
We prospectively studied the incidence and clinical course of hypertriglyceridemia and hypercholeste...
To access publisher's full text version of this article click on the hyperlink belowPurpose: Asparag...
L-asparaginase (L-Aspa) is utilized as a part of the therapy in children with acute lymphoblastic le...
AbstractL-asparaginase (L-ASPA) has been put to a wide application in many therapeutic protocols, ab...
Asparaginase is an integral component of multiagent chemotherapy regimens for the treatment of child...
One of the most common causes of acute pancreatitis in children is medications. These include L-aspa...
Background Survival for childhood acute lymphoblastic leukaemia surpasses 90% with contemporary ther...
l-Asparaginase (EC 3.5.1.1) was first used as a component of combination drug therapies to treat acu...
L-Asparaginase (L-Asp) is a critical component of chemotherapy for acute lymphoblastic leukemia (ALL...
Asparaginase is one of the most important chemotherapeutic agents against pediatric acute lymphoblas...
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects white blood cells and is a...
The history of asparaginase clinical use is inextricably linked to the improvement of treatment prog...
__Abstract__ Intensified and effective asparaginase therapy is very important in modern treatment...
L-Asparaginase-induced pancreatitis is an uncommon but potentially lethal complication. An 8-year-ol...
Asparaginase (ASP)-associated pancreatitis (AAP) occurs during acute lymphoblastic leukemia treatmen...
We prospectively studied the incidence and clinical course of hypertriglyceridemia and hypercholeste...
To access publisher's full text version of this article click on the hyperlink belowPurpose: Asparag...
L-asparaginase (L-Aspa) is utilized as a part of the therapy in children with acute lymphoblastic le...
AbstractL-asparaginase (L-ASPA) has been put to a wide application in many therapeutic protocols, ab...
Asparaginase is an integral component of multiagent chemotherapy regimens for the treatment of child...
One of the most common causes of acute pancreatitis in children is medications. These include L-aspa...
Background Survival for childhood acute lymphoblastic leukaemia surpasses 90% with contemporary ther...
l-Asparaginase (EC 3.5.1.1) was first used as a component of combination drug therapies to treat acu...
L-Asparaginase (L-Asp) is a critical component of chemotherapy for acute lymphoblastic leukemia (ALL...
Asparaginase is one of the most important chemotherapeutic agents against pediatric acute lymphoblas...
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects white blood cells and is a...
The history of asparaginase clinical use is inextricably linked to the improvement of treatment prog...
__Abstract__ Intensified and effective asparaginase therapy is very important in modern treatment...
L-Asparaginase-induced pancreatitis is an uncommon but potentially lethal complication. An 8-year-ol...
Asparaginase (ASP)-associated pancreatitis (AAP) occurs during acute lymphoblastic leukemia treatmen...
We prospectively studied the incidence and clinical course of hypertriglyceridemia and hypercholeste...
To access publisher's full text version of this article click on the hyperlink belowPurpose: Asparag...