ORA ANTIBIOTIC PROPHYLAXIS USE IN PATIENTS ADMITTED IN GENERAL SURGERY DEPARTMENT AT TERTIARY CARE TEACHING HOSPITAL IN HARYANA.

  Background: Antimicrobial agents are among the most widely used and misunderstood medications. Antibiotic-resistant bacteria have emerged as an unavoidable result of extensive use of antimicrobial medications, fuelling an ever-increasing demand for new treatments. Antimicrobial drug development, on the other hand, has slowed drastically, with only a handful of new drugs, few of which are unique, being developed, being introduced into clinical practice each year. The greatest strategy to control resistance is to reduce incorrect antibiotic use. Despite growing knowledge of the dangers of antibiotic abuse, overprescribing is nevertheless common, owing to patient demand, physician time constraints, and diagnostic ambiguity. If advances in the treatment of infectious diseases are to be maintained, physicians must become wiser and more resourceful. Methods: The present study was a prospective observational study conducted in the department of pharmacology in collaboration with the department of Surgery with the prior approval of Institutional Ethical committee. All data were retrieved from the patients’ case records. Using a convenient sampling method 100 adult patients who underwent surgical procedures in MMIMSR during the study period were taken. Results: A total of 100 patients admitted to the general surgery department of MMIMSR fulfilling the inclusion and exclusion criteria were enrolled. Out of 100 patients, 52(52%) were male and 48(48%) were female patients who underwent surgery and majority of the patients enrolled are between 48-58years (40%) years of age. Cholecystectomy (28%) was the most frequent performed surgery type followed by hernial repair (24%) and haemorrhoidectomy (14%) Among all cases, surgical antibiotic prophylaxis was recommended in 93(93%) patients. The most preferred route of administration of surgical antibiotic prophylaxis were parenteral route 100 (100%) and Ceftriaxone was most commonly prophylactically prescribed antibiotic. Conclusion: Surgical site infection are the most common nosocomial infections in surgical patients accounting for prolonged hospital stay, mortality and increased cost of care. According to the analysed results of our study and from view of literature present study provides us patterns of antibiotic usage in patients admitted in surgery wards