Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have resulted in the development of improved IL-2 formulations with IL-2 receptor bias and tissue-targeting properties. Several of these compounds are currently in clinical development and are ushering IL-2 therapy into the current era of cancer immunotherapy
Interleukin-2 (IL-2) exerts crucial functions during immune homeostasis via its effects on regulator...
We performed a phase Ia/Ib study of interleukin 2 (IL2) in patients with cancer. Single doses of IL2...
Interleukin 2 is a small cytokine with many important immune functions. It is used mainly as a T cel...
Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have...
The use of interleukin-2 (IL-2) for the stimulation of an effector immune response against metastati...
Interleukin 2 (IL-2) plays a fundamental role in both immune activation and tolerance and has revolu...
IL-2 is a powerful immune growth factor and it plays important role in sustaining T cell response. T...
Antibody-cytokine fusion proteins (immunocytokine) exert a potent anti-cancer effect; indeed, they t...
Tumour immunotherapy, and particularly immue checkpoint inhibitors, have resulted in considerable re...
In this review we shall discuss the biological rationale and the clinical findings obtained using In...
Interleukin-2 (IL-2) is a cytokine centrally involved in the regulation of immune tolerance and acti...
BackgroundInterleukin-2 (IL-2) plays a pivotal role in immune homeostasis due to its ability to stim...
Clinical trials have demonstrated that an increased number of effector cells, especially tumor-speci...
Despite the fact that different administration routes and delivery systems have been used for interl...
Activation of resting T cells induces synthesis of interleukin-2 (IL-2) and expression of its specif...
Interleukin-2 (IL-2) exerts crucial functions during immune homeostasis via its effects on regulator...
We performed a phase Ia/Ib study of interleukin 2 (IL2) in patients with cancer. Single doses of IL2...
Interleukin 2 is a small cytokine with many important immune functions. It is used mainly as a T cel...
Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have...
The use of interleukin-2 (IL-2) for the stimulation of an effector immune response against metastati...
Interleukin 2 (IL-2) plays a fundamental role in both immune activation and tolerance and has revolu...
IL-2 is a powerful immune growth factor and it plays important role in sustaining T cell response. T...
Antibody-cytokine fusion proteins (immunocytokine) exert a potent anti-cancer effect; indeed, they t...
Tumour immunotherapy, and particularly immue checkpoint inhibitors, have resulted in considerable re...
In this review we shall discuss the biological rationale and the clinical findings obtained using In...
Interleukin-2 (IL-2) is a cytokine centrally involved in the regulation of immune tolerance and acti...
BackgroundInterleukin-2 (IL-2) plays a pivotal role in immune homeostasis due to its ability to stim...
Clinical trials have demonstrated that an increased number of effector cells, especially tumor-speci...
Despite the fact that different administration routes and delivery systems have been used for interl...
Activation of resting T cells induces synthesis of interleukin-2 (IL-2) and expression of its specif...
Interleukin-2 (IL-2) exerts crucial functions during immune homeostasis via its effects on regulator...
We performed a phase Ia/Ib study of interleukin 2 (IL2) in patients with cancer. Single doses of IL2...
Interleukin 2 is a small cytokine with many important immune functions. It is used mainly as a T cel...
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