Tobacco smoke and its metabolites are carcinogens that increase tissue oxidative stress and induce target tissue inflammation. We hypothesized that genetic variation of inflammatory pathway genes plays a role in tobacco-related carcinogenesis and is modified by tobacco smoking. We evaluated the association of 12 single nucleotide polymorphisms of 8 inflammation-related genes with tobacco-related cancers (lung, oropharynx, larynx, esophagus, stomach, liver, bladder, and kidney) using 3 case-control studies from: Los Angeles (population-based; 611 lung and 553 upper aero-digestive tract cancer cases and 1,040 controls), Taixing, China (population-based; 218 esophagus, 206 stomach, 204 liver cancer cases, and 415 controls), and Memorial Sloan-...
Cigarette smoking and exposure to environmental tobacco smoke are well-known risk factors for urothe...
Bladder cancer is a complex disease with known environmental and genetic risk factors. We performed ...
The risk of colorectal cancer associated with smoking is unclear and may be influenced by genetic va...
Tobacco smoke and its metabolites are carcinogens that increase tissue oxidative stress and induce t...
Background: Tobacco smoking is a well-established risk factor for cancer in approximately 20 organ s...
Although many of the mechanisms induced by cigarette smoke are highly conserved in cancers in genera...
Tobacco smoke is the major environmental risk factor underlying lung carcinogenesis. However, approx...
Lung cancer and chronic obstructive pulmonary disease (COPD) are the leading causes of morbidity and...
Background: Genetic variants in nicotinic acetylcholine receptor and alcohol metabolism genes have b...
Background. Squamous cell lung cancer (SCLC) is the most common form of lung cancer among men smoker...
Introduction: Tobacco smoke contains many potentially harmful compounds that may act differently and...
<div><p>Several variations in the nicotinic receptor genes have been identified to be associated wit...
Non-small cell lung cancer is the most common type of lung cancer. Both environmental and genetic ri...
Cancer is a significant health problem in the Middle East and global population. It is well establis...
Cigarette smoking is associated with increased head and neck cancer (HNC) risk. Tobacco-related carc...
Cigarette smoking and exposure to environmental tobacco smoke are well-known risk factors for urothe...
Bladder cancer is a complex disease with known environmental and genetic risk factors. We performed ...
The risk of colorectal cancer associated with smoking is unclear and may be influenced by genetic va...
Tobacco smoke and its metabolites are carcinogens that increase tissue oxidative stress and induce t...
Background: Tobacco smoking is a well-established risk factor for cancer in approximately 20 organ s...
Although many of the mechanisms induced by cigarette smoke are highly conserved in cancers in genera...
Tobacco smoke is the major environmental risk factor underlying lung carcinogenesis. However, approx...
Lung cancer and chronic obstructive pulmonary disease (COPD) are the leading causes of morbidity and...
Background: Genetic variants in nicotinic acetylcholine receptor and alcohol metabolism genes have b...
Background. Squamous cell lung cancer (SCLC) is the most common form of lung cancer among men smoker...
Introduction: Tobacco smoke contains many potentially harmful compounds that may act differently and...
<div><p>Several variations in the nicotinic receptor genes have been identified to be associated wit...
Non-small cell lung cancer is the most common type of lung cancer. Both environmental and genetic ri...
Cancer is a significant health problem in the Middle East and global population. It is well establis...
Cigarette smoking is associated with increased head and neck cancer (HNC) risk. Tobacco-related carc...
Cigarette smoking and exposure to environmental tobacco smoke are well-known risk factors for urothe...
Bladder cancer is a complex disease with known environmental and genetic risk factors. We performed ...
The risk of colorectal cancer associated with smoking is unclear and may be influenced by genetic va...