TAS5315 suppresses the production of inflammatory cytokines in a mouse CIA model.
- Daichi Akasaka (14670684)
- Satoru Iguchi (14670687)
- Ryusuke Kaneko (14670690)
- Yohei Yoshiga (111997)
- Daisuke Kajiwara (14670693)
- Yoshinori Nakachi (14670696)
- Naruto Noma (14670699)
- Kenji Tanaka (692662)
- Atsushi Shimizu (1862)
- Fumihito Hosoi (2538544)
Publication date
February 2023
DOI Publisher
Public Library of Science (PLoS)Abstract
(a) Arthritis score in the CIA mouse model on day 15. Experimental arthritis induced by two immunizations using collagen and CFA. Mice were administered vehicle or TAS5315 once daily for 14 days from 6th day after the second immunization. b) TNF-α, IL-1β, and IL-6 levels in synovial fluid exudates on day 15. Data are presented as the mean ± SEM (n = 6–8 per group). *PPP (TIF)</p
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