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Globalization, technological advances, economic and geopolitical shocks, pandemics, and any number of novel or unanticipated events have one thing in common: they represent change and require dynamic responses and adaptation from organizations, teams, and individuals. A critical resource for individuals to be adaptive are broad skills relevant to varied organizational conditions. These adaptive skills have been discussed in diverse venues but rarely in the organizational literature. Also, most, if not all, of extant conceptual frameworks related to adaptive skills remain unvalidated. The purpose of this research was to organize these skills, define and situate them in the relevant organizational and psychological literatures, and empirically test a proposed four-category framework. The experimental results supported the C+MAC framework, as skills were better categorized in terms of their theoretically related category. Additionally, the four-category framework proved a better fit to the skills compared to an influential, alternative model. The findings’ implications are discussed, noting how an empirically validated framework can facilitate understanding of how individuals engage with organizational environments and organizations get their work done.