INCIDENCE, RISK FACTORS, AND OUTCOME OF SUSPECTED CENTRAL VENOUS CATHETER-RELATED INFECTIONS IN CRITICALLY ILL COVID-19 PATIENTS: A MULTICENTER RETROSPECTIVE COHORT STUDY
- Smit, J.M.
- Exterkate, L.
- Tienhoven, A.J. van
- Haaksma, M.E.
- Heldeweg, M.L.A.
- Fleuren, L.
- Thoral, P.
- Dam, T.A.
- Heunks, L.M.A.
- Gommers, D.
- Cremer, O.L.
- Bosman, R.J.
- Rigter, S.
- Wils, E.J.
- Frenzel, T.
- Vlaar, A.P.
- Dongelmans, D.A.
- Jong, R. de
- Peters, M.
- Kamps, M.J.A.
- Ramnarain, D.
- Nowitzky, R.
- Nooteboom, F.G.C.A.
- Ruijter, W. de
- Urlings-Strop, L.C.
- Smit, E.G.M.
- Mehagnoul-Schipper, D.J.
- Dormans, T.
- Jager, C.P.C. de
- Hendriks, S.H.A.
- Achterberg, S.
- Oostdijk, E.
- Reidinga, A.C.
- Festen-Spanjer, B.
- Brunnekreef, G.B.
- Cornet, A.D.
- Tempel, W. van den
- Boelens, A.D.
- Koetsier, P.
- Lens, J.
- Faber, H.J.
- Karakus, A.
- Entjes, R.
- Jong, P. de
- Rettig, T.C.D.
- Arbous, S.
- Vonk, B.
- Machado, T.
- Girbes, A.R.J.
- Sieswerda, E.
- Elbers, P.W.G.
- Tuinman, P.R.
DOIAbstract
Background: Aims of this study were to investigate the prevalence and incidence of catheter-related infection, identify risk factors, and determine the relation of catheter-related infection with mortality in critically ill COVID-19 patients. Methods: This was a retrospective cohort study of central venous catheters (CVCs) in critically ill COVID-19 patients. Eligible CVC insertions required an indwelling time of at least 48 hours and were identified using a full-admission electronic health record database. Risk factors were identified using logistic regression. Differences in survival rates at day 28 of follow-up were assessed using a log-rank test and proportional hazard model. Results: In 538 patients, a total of 914 CVCs were included. ...
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