Kajian Pustaka Montelukas: Pengobatan Asma Pada Anak

Chronic airway inflammation is a major characteristic of asthma. Montelukast is a class of leukotriene receptor antagonists (LTRA) which has the most widely used anti-inflammatory properties because it shows the best effectiveness and safety. Many in vitro and in vivo experimental clinical studies have been published in the last 10 years covering the effectiveness and safety of montelukast in childhood asthma of varying degrees of severity. Montelukast is used as an alternative monotherapy for the ICS class or as an adjunct to enhance the anti-inflammatory and sparing effects of corticosteroids. montelukast as a treatment for asthma in children can be given in cases of mild to moderate persistent asthma, wheezing due to viruses, asthma due to exercise, and intolerance of steroid use in children. The advantages of montelukast as monotherapy are fast onset in controlling asthma, low side effects, given once daily oral administration without the need for an inhaler thereby increasing pediatric patient compliance