Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of <i>DPC4</i> Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Hendrik Ungefroren
Björn Konukiewitz
Rüdiger Braun
Ulrich Friedrich Wellner
Tobias Keck
Jens-Uwe Marquardt

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Publication date

January 2023

DOI

10.3390/cancers15030581

Publisher

MDPI AG

Journal

Cancers

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related mortality worldwide, with a 5-year-survival rate below 10% that is the lowest of all cancer types [...

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Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of <i>DPC4</i> Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Abstract

Extracted data

Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of <i>DPC4</i> Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Abstract

Extracted data

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