This paper presents the technical development and subsequent testing of a Real-Time Locating System based on Ultra-Wideband signals, with the aim to appraise its potential implementation in a real industrial case. The system relies on a commercial Radio Indoor Positioning System, called Qorvo MDEK1001, which makes use of UWB RF technology to determine the position of RF-tags placed on an item of interest, which in turn is located in an area covered by specific fixed antennas (anchors). Testing sessions were carried out both in an Italian laboratory and in a real industrial environment, to determine the best configurations according to some selected performance indicators. The results support the adoption of the proposed solution in industri...