Bacteroidota in the cecum differ significantly between summer- and winter-mimicking conditions.

(A) Analysis of composition of microbiomes (ANCOM) was performed on the four major phyla that constitute the cecum and large intestine flora of CBA/N mice. Boxplots showing bacterial genera with significantly different relative abundances depending on seasonal conditions (LW, SC) (cecum, LW n = 22; SC n = 24). Plots show medians and interquartile ranges. W represents the number of null hypotheses rejected when statistics are performed to see if there is a difference between samples for a particular bacterium. (B) The Firmicutes/Bacteroidota (F/B) ratios in cecum (left) and large intestine (right) were compared between LW and SC conditions, respectively. Box plots show medians and interquartile ranges, and symbols indicate the significant differences by t-test (*; p < 0.05).