We present a sample introduction interface that allows direct on-chip processing of crude, large volume urine samples for the detection of Herpes Simplex Virus 2 (HSV-2). Sample introduction, cell lysis, DNA purification and sample volume reduction from a 600 μL urine sample down to a 10 μL elution volume were achieved in 7 min, offering great potential for use in point-of-care diagnostic devices
© The Royal Society of Chemistry 2016. Despite recent advances in microfluidic-based integrated diag...
A variety of automated sample-in-answer-out systems for in vitro molecular diagnostics have been pre...
Diagnosis of Schistosoma haematobium relies primarily on microscopical analysis of urine. The method...
Urine is a preferred specimen for nucleic acid-based detection of sexually transmitted infections (S...
This paper describes work delivered under the Innovation R&D Programme (National Measurement System,...
There is a growing need for rapid diagnostic methods to support stewardship of antibiotics. We desc...
Antibiotic resistance in urinary tract infections (UTIs) can cause significant complications without...
The potential of first-void (FV) urine as a non-invasive liquid biopsy for detection of human papill...
Development of a high throughput quantitative assay for detecting HSV DNA in clinical sample
Bacterial-based infectious disease, such as sexually transmitted infections and hospital-acquired in...
Abstract Background The speed and sensitivity of real-time polymerase chain reaction (PCR) have made...
Urine cell-free DNA (cfDNA) is a valuable non-invasive biomarker with broad potential clinical appli...
Background: Herpes simplex virus (HSV) is the most common cause of acute sporadic encephalitis in th...
Urine culture, the current gold standard for urinary tract infection (UTI) diagnosis, does not produ...
Extracellular vesicles (EVs) are cell-derived vesicles and play important role in intercellular comm...
© The Royal Society of Chemistry 2016. Despite recent advances in microfluidic-based integrated diag...
A variety of automated sample-in-answer-out systems for in vitro molecular diagnostics have been pre...
Diagnosis of Schistosoma haematobium relies primarily on microscopical analysis of urine. The method...
Urine is a preferred specimen for nucleic acid-based detection of sexually transmitted infections (S...
This paper describes work delivered under the Innovation R&D Programme (National Measurement System,...
There is a growing need for rapid diagnostic methods to support stewardship of antibiotics. We desc...
Antibiotic resistance in urinary tract infections (UTIs) can cause significant complications without...
The potential of first-void (FV) urine as a non-invasive liquid biopsy for detection of human papill...
Development of a high throughput quantitative assay for detecting HSV DNA in clinical sample
Bacterial-based infectious disease, such as sexually transmitted infections and hospital-acquired in...
Abstract Background The speed and sensitivity of real-time polymerase chain reaction (PCR) have made...
Urine cell-free DNA (cfDNA) is a valuable non-invasive biomarker with broad potential clinical appli...
Background: Herpes simplex virus (HSV) is the most common cause of acute sporadic encephalitis in th...
Urine culture, the current gold standard for urinary tract infection (UTI) diagnosis, does not produ...
Extracellular vesicles (EVs) are cell-derived vesicles and play important role in intercellular comm...
© The Royal Society of Chemistry 2016. Despite recent advances in microfluidic-based integrated diag...
A variety of automated sample-in-answer-out systems for in vitro molecular diagnostics have been pre...
Diagnosis of Schistosoma haematobium relies primarily on microscopical analysis of urine. The method...