Phosphosites increased >50% upon treatment of KO cells with either CX4945 (A) or GO286 (B). Phosphosites increased more than 50% in CK2α(-/-)/Δα’ cells after CX4945 treatment (A), GO286 treatment (B). Phosphosites present in both are shown in the bottom part of the table labeled as “CX4945 & GO289” (C). Red color denotes phosphosites that do not conform to the CK2 consensus
CK2 is a ubiquitous, constitutively active, highly pleiotropic, acidophilic Ser/Thr protein kinase w...
<p>(A) Schematic representation of <i>in silico</i> analysis of mouse Pax7 sequence, depicting Pax7 ...
<p>(A) Western blot analysis of nuclear extracts derived from HeLa cells growing asynchronously or a...
Wild-type (WT), CK2α(-/-)/Δα’, CK2α(-/-) and CK2α’(-/-) C2C12 cells were lysed. Cellular CK2 activit...
CK2 activity in cell lysates of C2C12 WT and CK2α(-/-)/Δα’ cells were tested as detailed in Material...
20 μg of each subcellular fraction (N, nuclei; Cyto, cytosol and MM, membranes) of wild-type (WT) or...
CK2 is a Ser/Thr protein kinase composed of two catalytic (alpha/alpha ') subunits and a non-catalyt...
CK2 denotes a ubiquitous and pleiotropic protein kinase whose holoenzyme is composed of two catalyti...
<p>(<b>A</b>) Volcano plot visualising quantified phospho-sites with significant differences between...
The acronym CK2 (derived from the misnomer "casein kinase-2") denotes a pleiotropic acidophilic prot...
CK2 is an extremely pleiotropic Ser/Thr protein kinase, responsible for the generation of a large pr...
<p>(A-D) Immunohistochemistry for phosphorylated STAT3 on Ser727 in normal reactive lymphoid tissue ...
<p>(A) From left to right the conditions for Kc cells subjected to phosphopeptide enrichment and mas...
Protein phosphorylation is a crucial regulatory mechanism that controls many aspects of cellular sig...
<p>A) <i>In vitro</i> phosphorylation of CKβ by protein kinase in 20 μg each of MCF-7 and HepG2 cell...
CK2 is a ubiquitous, constitutively active, highly pleiotropic, acidophilic Ser/Thr protein kinase w...
<p>(A) Schematic representation of <i>in silico</i> analysis of mouse Pax7 sequence, depicting Pax7 ...
<p>(A) Western blot analysis of nuclear extracts derived from HeLa cells growing asynchronously or a...
Wild-type (WT), CK2α(-/-)/Δα’, CK2α(-/-) and CK2α’(-/-) C2C12 cells were lysed. Cellular CK2 activit...
CK2 activity in cell lysates of C2C12 WT and CK2α(-/-)/Δα’ cells were tested as detailed in Material...
20 μg of each subcellular fraction (N, nuclei; Cyto, cytosol and MM, membranes) of wild-type (WT) or...
CK2 is a Ser/Thr protein kinase composed of two catalytic (alpha/alpha ') subunits and a non-catalyt...
CK2 denotes a ubiquitous and pleiotropic protein kinase whose holoenzyme is composed of two catalyti...
<p>(<b>A</b>) Volcano plot visualising quantified phospho-sites with significant differences between...
The acronym CK2 (derived from the misnomer "casein kinase-2") denotes a pleiotropic acidophilic prot...
CK2 is an extremely pleiotropic Ser/Thr protein kinase, responsible for the generation of a large pr...
<p>(A-D) Immunohistochemistry for phosphorylated STAT3 on Ser727 in normal reactive lymphoid tissue ...
<p>(A) From left to right the conditions for Kc cells subjected to phosphopeptide enrichment and mas...
Protein phosphorylation is a crucial regulatory mechanism that controls many aspects of cellular sig...
<p>A) <i>In vitro</i> phosphorylation of CKβ by protein kinase in 20 μg each of MCF-7 and HepG2 cell...
CK2 is a ubiquitous, constitutively active, highly pleiotropic, acidophilic Ser/Thr protein kinase w...
<p>(A) Schematic representation of <i>in silico</i> analysis of mouse Pax7 sequence, depicting Pax7 ...
<p>(A) Western blot analysis of nuclear extracts derived from HeLa cells growing asynchronously or a...