Calculating the adaptive/immune ratio.
- Johanne Ahrenfeldt (3165513)
- Ditte S. Christensen (14573627)
- Andreas B. Østergaard (14573630)
- Judit Kisistók (14573633)
- Mateo Sokač (14573636)
- Nicolai J. Birkbak (14573639)
Publication date
February 2023
DOI Publisher
Public Library of Science (PLoS)Abstract
a) A forest plot showing the hazard ratio for progression of cancer for the expression of each of the cell types in the TIL calculation. Yellow marks adaptive immune cells, purple marks the innate immune cells. b) A schematic showing how we calculate the A/I ratio. c) The mean A/I ratio for 29 cancer types in the TCGA cohort. The female mean ratio on the x-axis and male ratio is in the y axis. The size of the dot represents the p-value for the comparison of the mean. d) Univariate cox proportional hazard regression for the A/I ratio against progression free interval (PFI) across cancer types and genders for TCGA. e) Correlation of the A/I ratio and the TIL score across all cancer types in TCGA.</p
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