Circulating tissue inhibitor of metalloproteinases 1 (TIMP-1) at COVID-19 onset predicts severity status
- Brusa, Stefano
- Terracciano, Daniela
- Bruzzese, Dario
- Fiorenza, Mariano
- Stanziola, Lucia
- Pinchera, Biagio
- Valente, Valeria
- Gentile, Ivan
- Cittadini, Antonio
- Mormile, Ilaria
- Mormile, Mauro
- Portella, Giuseppe
DOIAbstract
Systemic biomarkers for severity of SARS-CoV-2 infection are of great interest. In this study, we evaluated a set of collagen metabolites and extracellular matrix remodeling biomarkers including procollagen type III amino terminal propeptide (PIIINP), tissue inhibitor of metalloproteinases 1 (TIMP-1) and hyaluronic acid (HA) as prognostic indicators in COVID-19 patients
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