Antimicrobial Compliance with CPAP in patients with obstructive sleep apnea: sleeping times with and without apparatus: A pilot study

Background: It has long been understood that Continuous Positive Airway Presssure CPAP adherence is not perfect in most patients, which may impact the long-term therapeutic benefits of treatment. This study aimed to investigate the sleep patterns and compliance with treatment of adults with obstructive sleep apnoea who are using CPAP and how these may affect the disease-modifying effects of CPAP. Methods: A cross-sectional analysis of CPAP compliance in patients with moderate-to-severe OSA. The data of patients visiting regional general practice were collected by a survey. Results: More than half (66%) of the participants recorded partial compliance with CPAP, removing the apparatus and returning to sleep without CPAP once per week or more. Most (83%) participants claimed that they were receiving four or more hours of CPAP therapy per night. For the sub-group with reduced CPAP compliance, the most significant factors which influenced use are mask discomfort (50%) and relief of daytime symptoms (63%). Conclusion: This study demonstrated that CPAP users who met the criteria for adequate adherence to treatment may still have periods of sleep when they were exposed to disease triggering apnoeic episodes. The research in future should compare the long-term benefits of CPAP on morbidity and mortality between groups with perfect and partial compliance with treatment