Active microcalcification of elastic fibers is a hallmark of pseudoxanthoma elasticum and it can be measured with the assessment of deposition of 18F-NaF using a PET/CT scan at the skin and vascular levels. It is not known whether this deposition changes over time in absence of specific therapy. We repeated in two years a PET/CT scan using 18F-NaF as a radiopharmaceutical in patients with the disease and compared the deposition at skin and vessel. Furthermore, calcium score values at the vessel wall were also assessed. Main results indicate in the vessel walls that calcification progressed in each patient; by contrast, the active microcalcification, measured and target-to-background ratio showed reduced active deposition. By contrast, at sk...
Despite improvements in treatment, patients with vascular disease are still at high risk for new car...
International audienceVascular calcification is a complex and dynamic process occurring in various p...
Background: Microcalcifications cannot be identified with the present resolution of CT; however, 18F...
Active microcalcification of elastic fibers is a hallmark of pseudoxanthoma elasticum and it can be ...
International audienceBACKGROUND: Pseudoxanthoma elasticum (PXE) is an inherited metabolic disease c...
Abstract Objectives Pseudoxanthoma elasticum (PXE) is a rare genetic disorder, characterised by elas...
BACKGROUND AND AIMS: Pseudoxanthoma elasticum (PXE) is a monogenetic disorder with progressive calci...
Background: Microcalcifications cannot be identified with the present resolution of CT; however, 18F...
Background and aims: The contribution of arterial calcification (AC) in peripheral arterial disease ...
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While ...
Background: Pseudoxanthoma elasticum (PXE), due to rare sequence variants in the ABCC6 gene, is char...
Vascular disease has a large worldwide medical burden. Even if all modifiable vascular risk factors ...
Background and aims: Patients with pseudoxanthoma elasticum (PXE), a monogenetic calcification disea...
Despite improvements in treatment, patients with vascular disease are still at high risk for new car...
International audienceVascular calcification is a complex and dynamic process occurring in various p...
Background: Microcalcifications cannot be identified with the present resolution of CT; however, 18F...
Active microcalcification of elastic fibers is a hallmark of pseudoxanthoma elasticum and it can be ...
International audienceBACKGROUND: Pseudoxanthoma elasticum (PXE) is an inherited metabolic disease c...
Abstract Objectives Pseudoxanthoma elasticum (PXE) is a rare genetic disorder, characterised by elas...
BACKGROUND AND AIMS: Pseudoxanthoma elasticum (PXE) is a monogenetic disorder with progressive calci...
Background: Microcalcifications cannot be identified with the present resolution of CT; however, 18F...
Background and aims: The contribution of arterial calcification (AC) in peripheral arterial disease ...
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While ...
Background: Pseudoxanthoma elasticum (PXE), due to rare sequence variants in the ABCC6 gene, is char...
Vascular disease has a large worldwide medical burden. Even if all modifiable vascular risk factors ...
Background and aims: Patients with pseudoxanthoma elasticum (PXE), a monogenetic calcification disea...
Despite improvements in treatment, patients with vascular disease are still at high risk for new car...
International audienceVascular calcification is a complex and dynamic process occurring in various p...
Background: Microcalcifications cannot be identified with the present resolution of CT; however, 18F...