Protein bound uremic toxins, such as p-cresol, cannot be effectively removed by conventional dialysis techniques and are accumulated in plasma, thus contributing to progression of both chronic kidney disease (CKD) and cardiovascular disease (CVD). Pathological effects of uremic toxins include activation of inflammatory response, endothelial dysfunction and release of endothelial microvesicles. To date, the role of p-cresol in endothelial microvesicles formation has not been analyzed. The aim of the present study was evaluate the effects of endothelial microvesicles released by p-cresol (PcEMV) on endothelial dysfunction. An in vitro model of endothelial damage mediated by p-cresol was proposed to evaluate the functional effect of PcEMV on t...
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair.B...
NEW FINDING: What is the central question of this study? Polyphenols shows protective cardiometaboli...
Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular complica...
Protein bound uremic toxins, such as p-cresol, cannot be effectively removed by conventional dialysi...
Cardiovascular disease is a major cause of mortality in chronic kidney disease patients. Indoxyl sul...
P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines.BackgroundIn...
33rd Annual Meeting of the American-Society-of-Nephrology, TORONTO, CANADA, OCT 10-16, 2000Internati...
Endothelial aging may be induced early in pathological situations. The uremic toxins indoxyl sulfate...
International audiencePatients with chronic renal failure (CRF) exhibit endothelial dysfunction, whi...
International audiencep-Cresyl sulfate (PCS), indoxyl sulfate (IS), and inorganic phosphate (Pi) are...
AIMS: Cresols are present in antiseptics, coal tar, some resins, pesticides, and industrial solvents...
Objective To investigate the effects of uremic toxin p-cresol (PC) on the oxidative stress of human ...
. These authors contributed equally to this work. Aims: Cresols are present in antiseptics, coal tar...
Endothelial progenitor cells are known to reverse acute kidney injury by paracrine mechanisms. We pr...
Endothelial progenitor cells are known to reverse acute kidney injury by paracrine mechanisms. We pr...
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair.B...
NEW FINDING: What is the central question of this study? Polyphenols shows protective cardiometaboli...
Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular complica...
Protein bound uremic toxins, such as p-cresol, cannot be effectively removed by conventional dialysi...
Cardiovascular disease is a major cause of mortality in chronic kidney disease patients. Indoxyl sul...
P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines.BackgroundIn...
33rd Annual Meeting of the American-Society-of-Nephrology, TORONTO, CANADA, OCT 10-16, 2000Internati...
Endothelial aging may be induced early in pathological situations. The uremic toxins indoxyl sulfate...
International audiencePatients with chronic renal failure (CRF) exhibit endothelial dysfunction, whi...
International audiencep-Cresyl sulfate (PCS), indoxyl sulfate (IS), and inorganic phosphate (Pi) are...
AIMS: Cresols are present in antiseptics, coal tar, some resins, pesticides, and industrial solvents...
Objective To investigate the effects of uremic toxin p-cresol (PC) on the oxidative stress of human ...
. These authors contributed equally to this work. Aims: Cresols are present in antiseptics, coal tar...
Endothelial progenitor cells are known to reverse acute kidney injury by paracrine mechanisms. We pr...
Endothelial progenitor cells are known to reverse acute kidney injury by paracrine mechanisms. We pr...
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair.B...
NEW FINDING: What is the central question of this study? Polyphenols shows protective cardiometaboli...
Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular complica...