SEOM clinical guidelines for anaplastic gliomas (2017).
- Balañá, C
- Alonso, M
- Hernandez-Lain, A
- Hernandez, A
- Perez-Segura, P
- Pineda, E
- Ramos, A
- Sanchez, A R
- Teixidor, P
- Verger, E
- Benavides, M
DOIAbstract
The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors
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