Major depressive disorder (MDD) is commonly diagnosed prior to adulthood, and when left untreated, may result in negative consequences that extend into adulthood. It is estimated that children and adolescents who suffer from MDD are more likely to develop conduct and anxiety disorders, and that up to 25% eventually develop substance abuse disorder. Consequently, this has resulted in a disproportionate increase in the prevalence of antidepressants prescribed to populations below 20 years of age, many of whom remain treatment-resistant. Recently, the non-competitive N-Methyl-D-aspartate (NMDA) receptor antagonist, ketamine, has been shown to alleviate symptoms of MDD in individuals that suffer from treatment-resistant depression. However, lit...
Background. Adolescent development of the prefrontal cortex (PFC) is accompanied by important change...
Objective: Pediatric depression is associated with significant functional impairment at school and a...
Adolescent development of the prefrontal cortex (PFC) is accompanied by important changes in glutama...
Pediatric depression was not well recognized until relatively recent. Today, however, major depressi...
Pediatric depression was not well recognized until relatively recent. Today, however, major depressi...
Early-life exposure to ketamine mediates an anxiolytic effect in adulthood. Epidemiological reports ...
Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent an...
Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent an...
Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, produces quick and effec...
Major Depressive Disorder (MDD) is one of the most severe and potentially debilitating forms of mood...
Approximately 10% of children and adolescents are diagnosed with major depressive disorder (MDD). Cu...
The National Institutes of Mental Health has portrayed major depressive disorder (MDD) to affect app...
Diagnosing pediatric populations with major depressive disorder (MDD) was almost unthinkable until s...
Accumulating preclinical evidence indicates that early-life exposure to psychotropic medications res...
The N-methyl-D-aspartate (NMDA) receptor antagonist ketamine is one of the most attractive antidepre...
Background. Adolescent development of the prefrontal cortex (PFC) is accompanied by important change...
Objective: Pediatric depression is associated with significant functional impairment at school and a...
Adolescent development of the prefrontal cortex (PFC) is accompanied by important changes in glutama...
Pediatric depression was not well recognized until relatively recent. Today, however, major depressi...
Pediatric depression was not well recognized until relatively recent. Today, however, major depressi...
Early-life exposure to ketamine mediates an anxiolytic effect in adulthood. Epidemiological reports ...
Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent an...
Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent an...
Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, produces quick and effec...
Major Depressive Disorder (MDD) is one of the most severe and potentially debilitating forms of mood...
Approximately 10% of children and adolescents are diagnosed with major depressive disorder (MDD). Cu...
The National Institutes of Mental Health has portrayed major depressive disorder (MDD) to affect app...
Diagnosing pediatric populations with major depressive disorder (MDD) was almost unthinkable until s...
Accumulating preclinical evidence indicates that early-life exposure to psychotropic medications res...
The N-methyl-D-aspartate (NMDA) receptor antagonist ketamine is one of the most attractive antidepre...
Background. Adolescent development of the prefrontal cortex (PFC) is accompanied by important change...
Objective: Pediatric depression is associated with significant functional impairment at school and a...
Adolescent development of the prefrontal cortex (PFC) is accompanied by important changes in glutama...