Identification of novel antifungal skeleton of hydroxyethyl naphthalimides with synergistic potential for chemical and dynamic treatments

  • Zhang, Pengli
  • Tangadanchu, Vijai Kumar Reddy
  • Zhou, Chenghe
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Publication date
December 2022
Publisher
Digital Commons@Becker
Language
English

Abstract

The invasion of pathogenic fungi poses nonnegligible threats to the human health and agricultural industry. This work exploited a family of hydroxyethyl naphthalimides as novel antifungal species with synergistic potential of chemical and dynamic treatment to combat the fungal resistance. These prepared naphthalimides showed better antifungal potency than fluconazole towards some tested fungi includin

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