Model of ribosome binding kinetics to a translation initiation region.
- Eric C. Dykeman (9922923)
Publication date
January 2023
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Kinetic model of 30S:PIC binding to a TIR region of an mRNA via standby and direct pathways. TIR regions are considered as being hairpin only regions, possibly flanked by multi-loop helices. k−F = 1/τu is the kinetic rate of TIR unfolding, while is the binding rate of 30S:PIC to the mRNA via ribosome protein S1. (B) Apparent 30S:PIC binding rate to TIR region at a cellular growth rate of μ = 0.7 doublings per hour.</p
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