Mutations in the spike protein of SARS-CoV-2 variants concentrate in regions of high epitope and accessibility scores.
- Sören von Bülow (10515004)
- Mateusz Sikora (257612)
- Florian E. C. Blanc (10515007)
- Roberto Covino (393172)
- Gerhard Hummer (90147)
Publication date
January 2023
DOI Publisher
Public Library of Science (PLoS)Abstract
Top views (A, B) and side views (C, D) of spike. Pink spheres show positions of Omicron BA.1 mutations, red spheres show positions unique to Omicron BA.5 mutations, and yellow spheres are those in earlier variants. Intense purple surface shading in A and C indicates high consensus epitope score [18]. Intense cyan surface shading in B and D indicates high AAS. Proteins were rendered with Visual Molecular Dynamics (VMD) v1.9.3 [19].</p
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