Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway

Pingping Sun
Yuemin Zhang
Lilan Sun
Na Sun
Jinguang Wang
Huagang Ma

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Publication date

January 2023

DOI

10.1186/s12905-022-02154-6

Publisher

Springer Science and Business Media LLC

Journal

BMC Women s Health

Abstract

Highlights 1. Kisspeptin expression is decreased in ovaries of PCOS rat 2. Kisspeptin promotes proliferation and inhibits apoptosis of granulosa cells 3. Kisspeptin alleviates oxidative stress of granulosa cells 4. Kisspeptin activates PI3K/AKT/ERK signalling pathwa

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Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway

Abstract

Extracted data

Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway

Abstract

Extracted data

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