Effect of diet on body weight and composition over four weeks.

A) Average weight by week, from the onset of experimental diets until 4 weeks across both cohort 1 and 2, CON (n = 36) and HF (n = 49). On week one and after, CON and HF weights are different (P<0.05), as determined by mixed model and post-hoc analysis. B) BMI measurements (ratio of weight to length) at the end of the four-week period, cohort 1 mice, CON (n = 18) and HF (n = 24). C) Percent fat, as measured by EchoMRI in cohort 2, CON (n = 18) and HF (n = 25). * indicates significant results (P < 0.05).