The table lists the intensities (Log2) of peptides—identified in the IP-MS interactome analysis. Each row contains the name of proteins that could be reconstructed from a set of identified peptides. The MS data analysis was done by the MaxQuant software. The protein Intensities are the Summed up extracted ion current of all isotopic clusters associated with the identified amino acid sequence. T tests analyses (two-tailed, paired done using Perseus software) was done between the proteins that were pulled down using specific antibodies (LHX2, BRG1, OTX2) compared to pulled down using nonspecific IgG. (XLSX)</p
A better understanding of the molecular mechanisms underlying disease is key for expediting the deve...
Immuno-precipitation (IP) experiments using MS provide a sensitive and accurate way of characterisin...
The field of proteomics encompasses the study of identities, interactions, and dynamics of all prote...
Protein interaction in cells can be described at different levels. At a low interaction level, prote...
Protein interaction in cells can be described at different levels. At a low interaction level, prote...
Protein interaction in cells can be described at different levels. At a low interaction level, pro...
Mapping protein-protein interactions is an invaluable tool for understanding protein function. Here,...
Identifying the partners of a given protein (the interactome) may provide leads about the protein’s ...
A typical high-sensitivity antibody affinity purification-mass spectrometry experiment easily identi...
Most proteins function as part of various complexes, forming via stable and dynamic protein–protein ...
Comprehensive protein-protein interaction network analysis can help reveal protein functions in a sy...
The reliable identification of protein interaction partners and how such interactions change in resp...
We present a mass spectrometry-based strategy for the absolute quantification of protein complex com...
<p>AC, accession code; PMF, peptide mass fingerprinting; obs, observed; calc, calculated; MW, molecu...
ABSTRACT: Mass spectrometry (MS)-based shotgun proteomics is an effective technology for global prot...
A better understanding of the molecular mechanisms underlying disease is key for expediting the deve...
Immuno-precipitation (IP) experiments using MS provide a sensitive and accurate way of characterisin...
The field of proteomics encompasses the study of identities, interactions, and dynamics of all prote...
Protein interaction in cells can be described at different levels. At a low interaction level, prote...
Protein interaction in cells can be described at different levels. At a low interaction level, prote...
Protein interaction in cells can be described at different levels. At a low interaction level, pro...
Mapping protein-protein interactions is an invaluable tool for understanding protein function. Here,...
Identifying the partners of a given protein (the interactome) may provide leads about the protein’s ...
A typical high-sensitivity antibody affinity purification-mass spectrometry experiment easily identi...
Most proteins function as part of various complexes, forming via stable and dynamic protein–protein ...
Comprehensive protein-protein interaction network analysis can help reveal protein functions in a sy...
The reliable identification of protein interaction partners and how such interactions change in resp...
We present a mass spectrometry-based strategy for the absolute quantification of protein complex com...
<p>AC, accession code; PMF, peptide mass fingerprinting; obs, observed; calc, calculated; MW, molecu...
ABSTRACT: Mass spectrometry (MS)-based shotgun proteomics is an effective technology for global prot...
A better understanding of the molecular mechanisms underlying disease is key for expediting the deve...
Immuno-precipitation (IP) experiments using MS provide a sensitive and accurate way of characterisin...
The field of proteomics encompasses the study of identities, interactions, and dynamics of all prote...