Reakce imunitního systému na spirochéty Lymské boreliózy v závislosti na jejich patogenním potenciálu

An infectious disease known as Lyme borreliosis is caused by the bacterium Borrelia, which is transmitted to humans by ticks. The bachelor thesis deals with the comparison of the pathogenic potential of three species of bacteria from the Borrelia burgdorferi sensu lato complex, which are characterized by their antigenic equipment. Differences between these species result in different responses of the host immune system and also affect tissue specificity, it determines the target area in the body where a given bacterium persists and causes symptoms typical of its species