The novel kinetoplastid kinesin TbKIFx and its partner TbPH1 are associated with specific cytoskeletal structures of Trypanosoma brucei

This study focuses on the kinesin motor protein TbKIFx and its presumably catalytically inactive partner TbPH1 in Trypanosoma brucei. Not much is known about the TbPH1/TbKIFx dimer so far. The aim of our research was to localize TbKIFx/TbPH1 in procyclic and bloodstream cells and to investigate potential cargo candidates. We believe that we identified the microtubule quartet and mature basal body as potential binding sites of TbKIFx/TbPH1 in both life cycle stages of T. brucei. However, our investigations into tyrosine-phosphorylated proteins as possible cargo of TbKIFx/TbPH1 remain inconclusive