This master thesis is focused on analysis of involvement of adaptive immunity during antitumour MBTA immunotherapy which is based on synergy of TLR agonist, anti-CD40 and phagocytosis stimulating ligands anchored into the tumour cells membrane. This immunotherapy was tested in murine pancreatic adenocarcinoma Panc02 model. The aims of this thesis were to analyse the tumor infiltration during therapy and examine the role of adaptive immunity using KO mice. Subsequently, the possibilities of strengthening immunotherapeutic effects using inhibitor of survivin YM155, betaglucans or anti-TGF in metastatic murine Panc02 model were tested
Pancreatic cancer remains deadly. High mortality is attributable to the inability to detect this can...
The main goal of this thesis was to study cancer immunotherapy based on combination of ligands of TL...
The main aim of this thesis was to study the role of regulatory T cells in cancer. Their presence, i...
This thesis is focused on analysis of immune processes during cancer immunotherapy which is based on...
This thesis is focused on immunotherapy of pancreatic adenocarcinoma which is based on the synergy o...
This study examines the role of innate and adaptive immunity in the immunotherapy based on the combi...
The aim of this thesis is focused on possibilities of cancer immunotherapy which was studied in mous...
The aim of this RNDr. Thesis is focused on understanding therapeutic potentials and limitations of t...
The aim of this thesis was to study murine melanoma B16-F10 therapy based on activation of both inna...
The aim of this thesis is to improve the therapeutic effect of the immunotherapy based on the synerg...
This master's thesis studies the efficacy of cancer immunotherapy based on TLR agonists and ligands ...
The aim of this thesis was to study cancer immunotherapy based on combination of TLR7 signalling and...
The aim of thesis was to study murine melanoma B16- F10 therapy based on the use of TLR agonists com...
This thesis deals with an immunotherapeutic strategy based on combination of TLR agonists, the ligan...
This dissertation examines the study of intratumoral cancer immunotherapy using a combination of ph...
Pancreatic cancer remains deadly. High mortality is attributable to the inability to detect this can...
The main goal of this thesis was to study cancer immunotherapy based on combination of ligands of TL...
The main aim of this thesis was to study the role of regulatory T cells in cancer. Their presence, i...
This thesis is focused on analysis of immune processes during cancer immunotherapy which is based on...
This thesis is focused on immunotherapy of pancreatic adenocarcinoma which is based on the synergy o...
This study examines the role of innate and adaptive immunity in the immunotherapy based on the combi...
The aim of this thesis is focused on possibilities of cancer immunotherapy which was studied in mous...
The aim of this RNDr. Thesis is focused on understanding therapeutic potentials and limitations of t...
The aim of this thesis was to study murine melanoma B16-F10 therapy based on activation of both inna...
The aim of this thesis is to improve the therapeutic effect of the immunotherapy based on the synerg...
This master's thesis studies the efficacy of cancer immunotherapy based on TLR agonists and ligands ...
The aim of this thesis was to study cancer immunotherapy based on combination of TLR7 signalling and...
The aim of thesis was to study murine melanoma B16- F10 therapy based on the use of TLR agonists com...
This thesis deals with an immunotherapeutic strategy based on combination of TLR agonists, the ligan...
This dissertation examines the study of intratumoral cancer immunotherapy using a combination of ph...
Pancreatic cancer remains deadly. High mortality is attributable to the inability to detect this can...
The main goal of this thesis was to study cancer immunotherapy based on combination of ligands of TL...
The main aim of this thesis was to study the role of regulatory T cells in cancer. Their presence, i...