This thesis concerns itself with the long-term behavior of generalized Langevin dynamics with multiplicative noise, i.e. the solutions to a class of two-component stochastic differential equations in \( \mathbb{R}^{d_1}\times\mathbb{R}^{d_2} \) subject to outer influence induced by potentials \( \Phi \) and \( \Psi \), where the stochastic term is only present in the second component, on which it is dependent. In particular, convergence to an equilibrium defined by an invariant initial distribution \( \mu \) is shown for weak solutions to the generalized Langevin equation obtained via generalized Dirichlet forms, and the convergence rate is estimated by applying hypocoercivity methods relying on weak or classical Poincaré inequaliti...