The main focus of this thesis is on modeling, performance evaluation and system-level optimization of next-generation cellular networks by using stochastic geometry. In addition, the emerging technology of Reconfigurable Intelligent Surfaces (RISs) is investigated for application to future wireless networks. In particular, relying on a Poisson-based abstraction model for the spatial distribution of nodes and access points, this thesis develops a set of new analytical frameworks for the computation of important performance metrics, such as the coverage probability and potential spectral efficiency, which can be used for system-level analysis and optimization. More specifically, a new analytical methodology for the analysis of three-dimension...