Numerical simulators are widely used to model physical phenomena and global sensitivity analysis (GSA) aims at studying the global impact of the input uncertainties on the simulator output. To perform GSA, statistical tools based on inputs/output dependence measures are commonly used. We focus here on the Hilbert-Schmidt independence criterion (HSIC). Sometimes, the probability distributions modeling the uncertainty of inputs may be themselves uncertain and it is important to quantify their impact on GSA results. We call it here the second-level global sensitivity analysis (GSA2). However, GSA2, when performed with a Monte Carlo double-loop, requires a large number of model evaluations, which is intractable with CPU time expensive simulator...