Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds of natural or anthropogenic origin. Biological life can for instance respond to chemical stressors by changes in gene expression, and thus, certain gene transcripts can potentially function as biomarkers, i.e. early warnings, of toxicity and chemical stress. A major challenge for biomarker application is the extrapolation of transcriptional data to potential effects at the organism level or above. Importantly, successful biomarker use also requires basal understanding of how to distinguish actual responses from background noise. The aim of this thesis is, based on response magnitude and variation, to evaluate the biomarker potential in a set ...
The cytochrome P450 pathway and antioxidant responses are known for their responsiveness to environm...
Marine bivalves have a set of unique capabilities to adapt to the complicated conditions owing to th...
Proceedings of the 1997 Georgia Water Resources Conference, March 20-22, 1997, Athens, Georgia.Bival...
Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds ...
Through a systematic review and a series of meta-analyses, we evaluated the general responsiveness o...
Background data and supplementary figures for the paper 'Transcriptional responses as biomarker...
We tested concentration-dependence of selected gene transcripts (cat, gst, hsp70, hsp90, mt and sod)...
Data for the paper 'Evaluation of transcriptional biomarkers using a high-resolution regression...
Using a selection of molecular biomarkers, we evaluated responses in freshwater mussels (Anodonta an...
Molecular biomarkers, like gene transcripts or enzyme activities, are potentially powerful tools for...
Data for the paper 'Molecular biomarker responses in the freshwater mussel Anodonta anatina exp...
Abstract Environmental pollution is increasing in coastal areas and is responsible for adverse hea...
Abstract Background Mixtures of chemicals present in aquatic environments may elicit toxicity due to...
Despite the increasing use of mussels in environmental monitoring and ecotoxicological studies, thei...
Ecological risk assessment (ERA) is a framework for monitoring risks of exposure and adverse effects...
The cytochrome P450 pathway and antioxidant responses are known for their responsiveness to environm...
Marine bivalves have a set of unique capabilities to adapt to the complicated conditions owing to th...
Proceedings of the 1997 Georgia Water Resources Conference, March 20-22, 1997, Athens, Georgia.Bival...
Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds ...
Through a systematic review and a series of meta-analyses, we evaluated the general responsiveness o...
Background data and supplementary figures for the paper 'Transcriptional responses as biomarker...
We tested concentration-dependence of selected gene transcripts (cat, gst, hsp70, hsp90, mt and sod)...
Data for the paper 'Evaluation of transcriptional biomarkers using a high-resolution regression...
Using a selection of molecular biomarkers, we evaluated responses in freshwater mussels (Anodonta an...
Molecular biomarkers, like gene transcripts or enzyme activities, are potentially powerful tools for...
Data for the paper 'Molecular biomarker responses in the freshwater mussel Anodonta anatina exp...
Abstract Environmental pollution is increasing in coastal areas and is responsible for adverse hea...
Abstract Background Mixtures of chemicals present in aquatic environments may elicit toxicity due to...
Despite the increasing use of mussels in environmental monitoring and ecotoxicological studies, thei...
Ecological risk assessment (ERA) is a framework for monitoring risks of exposure and adverse effects...
The cytochrome P450 pathway and antioxidant responses are known for their responsiveness to environm...
Marine bivalves have a set of unique capabilities to adapt to the complicated conditions owing to th...
Proceedings of the 1997 Georgia Water Resources Conference, March 20-22, 1997, Athens, Georgia.Bival...