Add to ORKGAmides are generally robust and hydrolytically resistant due to the nN-to-π*C=O conjugation. Twisted amides represent an unusual subclass of amides containing distorted, non-planar amide bonds as a consequence of geometric, steric or electronic effects. The most common approach to twisting the amide bond involves geometric constraint in the bridged bicyclic amide structure. Due to the disrupted amide resonance, twisted amides feature distinct reactivities compared to normal amides, including enhanced N-nucleophilicity, carbonyl-electrophilicity and “amino-ketone” reactivity. Despite the unusual structure and unique reactivity of twisted amides, their potential as monomers in polymerization has rarely been explored. In this dissertation, the...
Polyolefins, polyaromatics, polyesters, and polyethers comprise 63% of plastics worldwide. Their uti...
The amide bond represents one of the most important functional motifs in chemistry and biology. Howe...
The n-butyramido, isobutyramido, benzamido, and furancarboxamido functions profoundly modulate the e...
Since the seminal studies by Pauling in 1930s, planarity has become the defining characteristic of t...
The research presented herein describes the development of synthetic methods to one-carbon bridged t...
The first living polymerization of twisted amides is reported, achieved using simple primary alkyl i...
The importance of the amide bond cannot be overstated. Typical amides are planar structures, however...
The synthesis, crystal structures, and reactivity of the most twisted acyclic amides described to da...
The amide bond is one the most important functional motifs in chemistry and biology. However, despit...
The synthesis of amides is extremely important given the ubiquitous presence of this motif in biolog...
This dissertation describes the development of reaction methodologies that utilize unconventional bu...
In the past, aminocyclohexanol rings have been successfully utilized as pH-triggered molecular switc...
This dissertation describes the development of synthetic methodologies and approaches that leverage ...
The straightforward protonation of lactams by treatment with acid and the full structural characteri...
This thesis outlines work carried out in the last three years concerning the development of novel, a...
Polyolefins, polyaromatics, polyesters, and polyethers comprise 63% of plastics worldwide. Their uti...
The amide bond represents one of the most important functional motifs in chemistry and biology. Howe...
The n-butyramido, isobutyramido, benzamido, and furancarboxamido functions profoundly modulate the e...
Since the seminal studies by Pauling in 1930s, planarity has become the defining characteristic of t...
The research presented herein describes the development of synthetic methods to one-carbon bridged t...
The first living polymerization of twisted amides is reported, achieved using simple primary alkyl i...
The importance of the amide bond cannot be overstated. Typical amides are planar structures, however...
The synthesis, crystal structures, and reactivity of the most twisted acyclic amides described to da...
The amide bond is one the most important functional motifs in chemistry and biology. However, despit...
The synthesis of amides is extremely important given the ubiquitous presence of this motif in biolog...
This dissertation describes the development of reaction methodologies that utilize unconventional bu...
In the past, aminocyclohexanol rings have been successfully utilized as pH-triggered molecular switc...
This dissertation describes the development of synthetic methodologies and approaches that leverage ...
The straightforward protonation of lactams by treatment with acid and the full structural characteri...
This thesis outlines work carried out in the last three years concerning the development of novel, a...
Polyolefins, polyaromatics, polyesters, and polyethers comprise 63% of plastics worldwide. Their uti...
The amide bond represents one of the most important functional motifs in chemistry and biology. Howe...
The n-butyramido, isobutyramido, benzamido, and furancarboxamido functions profoundly modulate the e...