AbstractHere we report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network (BICCN). This was achieved by coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties and cellular resolution input–output mapping, integrated through cross-modal computational analysis. Our results advance the collective knowledge and understanding of brain cell-type organization1–5. First, our study reveals a unified molecular genetic landscape of cortical cell types that integrates their transcriptome, open chromatin...
Single cell transcriptomics has transformed the characterization of brain cell identity by providing...
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally cons...
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally cons...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
ABSTRACT We report the generation of a multimodal cell census and atlas of the mammalian primary mot...
We report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex...
We report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
AbstractSingle-cell transcriptomics can provide quantitative molecular signatures for large, unbiase...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
Single cell transcriptomics has transformed the characterization of brain cell identity by providing...
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally cons...
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally cons...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
ABSTRACT We report the generation of a multimodal cell census and atlas of the mammalian primary mot...
We report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex...
We report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex...
Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor c...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
AbstractSingle-cell transcriptomics can provide quantitative molecular signatures for large, unbiase...
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased sample...
Single cell transcriptomics has transformed the characterization of brain cell identity by providing...
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally cons...
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally cons...