Impact of COVID-19 on Outcomes of Patients Hospitalized with STEMI: A Nationwide Propensity-Matched Analysis.

INTRODUCTION: Patients with ST-segment elevation myocardial infarction (STEMI) and concurrent coronavirus disease 2019 (COVID-19) have been reported to have poor outcomes. However, previous studies are small and limited. METHODS: The National Inpatient Sample (NIS) database for the year 2020 was queried to identify all adult hospitalizations with a primary diagnosis of STEMI, with and without concurrent COVID-19. A 1:1 propensity score matching was performed. RESULTS: A total of 159,890 hospitalizations with a primary diagnosis of STEMI were identified. Of these, 2,210 (1.38%) had concurrent COVID-19. After propensity matching, STEMI patients with concurrent COVID-19 had a significantly higher mortality (17.8% vs 9.1%, OR 1.96, p CONCLUSION: STEMI patients with concurrent COVID-19 infection had a significantly higher (almost two times) in-hospital mortality, and lower likelihood of receiving same-day PCI, overall (any-day) PCI, and CABG during their admission, compared with STEMI patients without COVID-19