Hairball network diagram for 233 significant medication pairs.

The 233 significant medication pairs, consisting of 69 unique medications, are visualized as a hairball network diagram where each vertex indicates a medication (69 unique medications resulting in 69 vertices). Each of the vertices is linked via an edge if two medications are medication pairs with a high AKI correlation (233 significant medication pairs resulting in 233 edges). The width of the edges represents the administration frequency (0 − 50; 50 − 500; >500). The color of the edges shows the strength of Pearson similarity coefficients for the medication pairs (correlation coefficient of >0.08 is red, 0.07−0.08 is orange, and 0.07is grey). The size of the vertices represents the administration frequency of the single medications (0 − 20; 20 − 100; >100). The color of the vertices shows the strength of Pearson similarity coefficients for the isolated medications (red: Correlation coefficients >0.12; orange: 0.07− 0.12; white: Not significant or never administered alone). (TIF)