Mice were i.c.v administrated with β-PAE(1mg/kg) or saline at the onset of CLP model. ML385 was i.c.v injected 2h post-CLP. Data are shown as percentage survival after 7 days. The presented data are a composite of three independent experiments (n = 15 in each group). *Pvs. CLP group.</p
<p><b>A</b>) Mice were subcutaneously infected with 2×10<sup>7</sup> CFU <i>S. pyogenes</i> bacteria...
(B) The survival rates of WT mice receiving WT or TLR9 DCs were monitored for 6 d after CLP (23 mice...
<p>3 month-old mice (n = 42) were subjected to trauma and hemorrhage (TH) at −48 h followed by mild ...
<p>(A) During the first septic assault, after CLP and prior to <i>P</i>. <i>aeruginosa</i> instillat...
<p>CLP was performed as described in <i>Methods</i> and animals were treated with i.v saline 4 h pos...
<p>Baicalin improves survival of polymicrobial sepsis in CLP mice. In the bai group, mice were treat...
<p>CLP-induced mice were treated with or without CORM-2. Mouse survival was monitored for up to 72 h...
<p>Sham-operated untreated mice presented a 100% survival rate throughout the analyzed period of 120...
(B) 12 and 18 h after CLP, WT mice received 100 μg iCpG or control ODN, and survival rates were moni...
Dilutions of blood (B) or peritoneal lavage fluid (C) obtained from TLR9 or WT mice 12 h after CLP w...
<p>Mice were randomly divided into four groups (ten mice/group): sham, CLP, CLP plus Ig Fc, and CLP ...
<p>Seven day survival of CLP mice, CLP mice receiving HFIP immediately after CLP induction (CLP+HFIP...
<p>CLP was induced in mice, three groups were analyzed: 1- CLP without any treatment; 2- CLP with no...
<p>(A) WT (open symbols) and CCR4<sup>-/-</sup> (filled symbols) mice underwent sham (square) or L-C...
<p>Cecal ligation and puncture induced sepsis was performed with PTEN hepatocyte deficient and wildt...
<p><b>A</b>) Mice were subcutaneously infected with 2×10<sup>7</sup> CFU <i>S. pyogenes</i> bacteria...
(B) The survival rates of WT mice receiving WT or TLR9 DCs were monitored for 6 d after CLP (23 mice...
<p>3 month-old mice (n = 42) were subjected to trauma and hemorrhage (TH) at −48 h followed by mild ...
<p>(A) During the first septic assault, after CLP and prior to <i>P</i>. <i>aeruginosa</i> instillat...
<p>CLP was performed as described in <i>Methods</i> and animals were treated with i.v saline 4 h pos...
<p>Baicalin improves survival of polymicrobial sepsis in CLP mice. In the bai group, mice were treat...
<p>CLP-induced mice were treated with or without CORM-2. Mouse survival was monitored for up to 72 h...
<p>Sham-operated untreated mice presented a 100% survival rate throughout the analyzed period of 120...
(B) 12 and 18 h after CLP, WT mice received 100 μg iCpG or control ODN, and survival rates were moni...
Dilutions of blood (B) or peritoneal lavage fluid (C) obtained from TLR9 or WT mice 12 h after CLP w...
<p>Mice were randomly divided into four groups (ten mice/group): sham, CLP, CLP plus Ig Fc, and CLP ...
<p>Seven day survival of CLP mice, CLP mice receiving HFIP immediately after CLP induction (CLP+HFIP...
<p>CLP was induced in mice, three groups were analyzed: 1- CLP without any treatment; 2- CLP with no...
<p>(A) WT (open symbols) and CCR4<sup>-/-</sup> (filled symbols) mice underwent sham (square) or L-C...
<p>Cecal ligation and puncture induced sepsis was performed with PTEN hepatocyte deficient and wildt...
<p><b>A</b>) Mice were subcutaneously infected with 2×10<sup>7</sup> CFU <i>S. pyogenes</i> bacteria...
(B) The survival rates of WT mice receiving WT or TLR9 DCs were monitored for 6 d after CLP (23 mice...
<p>3 month-old mice (n = 42) were subjected to trauma and hemorrhage (TH) at −48 h followed by mild ...