Prognostic Score in Radiotherapy Practice for Palliative Treatments (PROPHET) Study for Bone Metastases: An Investigation Into the Clinical Effect on Treatment Prescription
- Francesco Cellini, MD
- Alessia Di Rito, MD
- Giambattista Siepe, MD
- Francesco Pastore, MD
- Elisabetta Lattanzi, MD
- Ilaria Meaglia, MD
- Angelo Tozzi, MD
- Stefania Manfrida, MD
- Silvia Longo, MD
- Simonetta Saldi, MD
- Raffaele Cassese, MD
- Fabio Arcidiacono, MD
- Michele Fiore, MD
- Valeria Masiello, MD
- Ciro Mazzarella, MD
- Antonio Diroma, MD
- Francesco Miccichè, MD
- Francesca Maurizi, MD
- Luca Dominici, MD
- Marta Scorsetti, MD
- Mario Santarelli, MD
- Vincenzo Fusco, MD
- Cynthia Aristei, MD
- Francesco Deodato, MD
- Maria A. Gambacorta, MD, PhD
- Ernesto Maranzano, MD
- Paolo Muto, MD
- Vincenzo Valentini, MD
- Alessio G. Morganti, MD
- Lorenza Marino, MD
- Costanza M. Donati, MD
- Rossella Di Franco, MD
DOIAbstract
Purpose: Bone metastases frequently occur during malignant disease. Palliative radiation therapy (PRT) is a crucial part of palliative care because it can relieve pain and improve patients’ quality of life. Often, a clinician's survival estimation is too optimistic. Prognostic scores (PSs) can help clinicians tailor PRT indications to avoid over- or undertreatment. Although the PS is supposed to aid radiation oncologists (ROs) in palliative-care scenarios, it is unclear what type of support, and to what extent, could impact daily clinical practice. Methods and Materials: A national-based investigation of the prescriptive decisions on simulated clinical cases was performed in Italy. Nine clinical cases from real-world clinical practice were ...
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